Abstract / Description: 

Background/objectives: Excess gestational weight gain (GWG) is a risk factor for maternal postpartum weight retention and excessive neonatal adiposity, especially in women with overweight or obesity. Whether lifestyle interventions to reduce excess GWG also reduce 12-month maternal postpartum weight retention and infant weight-for-length†z†score is unknown. Randomized controlled trials from the LIFE-Moms consortium investigated lifestyle interventions that began in pregnancy and tested whether there was benefit through 12 months on maternal postpartum weight retention. Subjects/methods: In LIFE-Moms, women (N?=?1150; 14.1 weeks gestation at enrollment) with overweight or obesity were randomized within each of seven trials to lifestyle intervention or standard care. Conclusion: Compared with standard care, lifestyle interventions initiated in pregnancy and focused on healthy eating, increased physical activity, and other behavioral strategies resulted in significantly less weight retention but similar infant anthropometric outcomes at 12 months postpartum in a large, diverse US population of women with overweight and obesity.

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Suzanne Phelan; Rebecca G. Clifton; Debra Haire-Joshu; Leanne M. Redman; Linda Van Horn; Mary Evans; Kaumudi Joshipura; Kimberly A. Couch; S. Sonia Arteaga; Alison G. Cahill; Kimberly L. Drews; Paul W. Franks; Dympna Gallagher; Jami L. Josefson; Samuel Klein; William C. Knowler; Corby K. Martin; Alan M. Peaceman; Elizabeth A. Thom; Rena R. Wing; Susan Z. Yanovski; Xavier Pi-Sunyer; The LIFE-Moms Research Group