Maternal Cardiovascular Complications at the Time of Delivery and Subsequent Re-Hospitalization in the United States, 2010 to 2016
Aims: Cardiovascular (CV) complications are the leading cause of maternal morbidity and mortality. The objective was to estimate trends in incidence of peripartum CV complications in the United States between 2010-2016. Methods and Results: This was a retrospective analyses using data from the Healthcare Cost and Utilization Project. We included women with delivery codes consistent with delivery, weighted to a national estimate. The primary outcome was the age-adjusted incidence of CV complications among all deliveries, including complications that occurred during re-hospitalizations. Complications were identified using International Classification of Diseases (ICD) codes. Joinpoint regression was used to evaluate time trends and complications were stratified by type. The secondary outcome was in-hospital maternal death among women with a CV complication. Conclusion: Our analyses suggest the rate of peripartum CV complications are increasing in the United States, which highlights the need for active efforts in research and prevention.